Identifying Stabilizers of Plasmid DNA for Pharmaceutical Use
Article in Journal of Pharmaceutical Sciences
Volume 99 (7), July 2010
Use of JMP® for Optimizing a Custom Peptide Microarray to Identify
Autoantibodies for Multiple Sclerosis
Article available online
August 2009
Gene Based Vaccines: Optimising Development and Delivery – A Marcus Evans Conference
Article in IDrugs
Volume 13 (10), November 2010, pp 759-761
Multiple sclerosis therapies: molecular mechanisms and future
Article in Results and Problems in Cell Differentiation
Volume 51, 2010, pp 259-285
Developing Combination Immunotherapies for Type 1 Diabetes: Recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group
Article in Clinical & Experimental Immunology
Volume 160 (2), May 2010, pp 176-184
DNA Vaccines for Autoimmune Diseases
Article in Expert Review of Vaccines
Volume 8 (9), September 2009, pp 1195-1203
Identifying stabilizers of plasmid DNA for pharmaceutical use
Zeng Y, Ramsey JD, King R, Leviten M, McGuire R, Volkin DB, Joshi SB, Middaugh CR.
Journal of Pharmaceutical Sciences Aug 25, 2010
Use of JMP for Optimizing a Custom Peptide Microarray to Identify Autoantibodies for Multiple Sclerosis
Rahman, A., W. Robinson, H. Garren, R. King, T. Kaysser-Kranich, C. Shafer, B. Knipmeyer
Published August 2009
online here
Improved Efficacy of a Tolerizing DNA Vaccine for Reversal of Hyperglycemia through Enhancement of Gene Expression and Localization to Intracellular Sites
Article in Journal of Immunology
Volume
181, pp 8298-8307, December 2008
A DNA Vaccine for Multiple Sclerosis
Article in Expert Opinion
Volume 8, pp 1539-1550, October 2008
Phase 2 Trial DNA Vaccine Encoding Myelin Basic Protein for Multiple Sclerosis
Article in Annals of Neurology, In Press
Volume 63, pp 611-620, May 2008
“Induction of Antigen-Specific Tolerance in Multiple Sclerosis After
Immunization With DNA Encoding Myelin Basic Protein in a Randomized,
Placebo-Controlled Phase 1/2 Trial”
Article in Archives of Neurology
Volume 64 (NO. 10), pp. 1407-1415, October 2007
“Phase I/II trial of a MBP encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin for treatment of MS”
Poster number PP14-22 presented at the 8th International Congress of Neuroimmunology, Nagoya, Japan, October 15-19, 2006
Antigen-specific immunomodulation in multiple sclerosis patients treated with MBP
encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin
Poster presented at
21st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Thessaloniki, Greece, September 28 – October 1, 2005.
Antigen-Specific Therapies in Multiple Sclerosis: Going Beyond Proteins and Peptides
International Reviews of Immunology, 24:415-446, 2005
An Immunomodulatory GpG Oligonucleotide for the Treatment of Autoimmunity via the Innate and Adaptive Immune Systems.
Article in
The Journal of Immunology, 2003, 171: 4920-4926
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
Article in
Nature, Biotechnology
Volume 21, Issue 9, September 2003
Autoantigen microarrays for multiplex characterization of autoantibody responses
Article in
Nature Medicine
Volume 8 Number 3 March 2002
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination
Article in Proceedings National Academy of Sciences
February 18, 2003, Volume 100, No 4, 1867 - 1872
The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease
Article in Science
Volume 294 23 November 2001
Immunization with DNA Encoding an Immunodominant Peptide of Insulin Prevents Diabetes in NOD Mice
Article in Clinical Immunology
Volume 100, No.2, August, pp. 164-171, 2001
Combination of Gene Delivery and DNA Vaccination to Protect from and Reverse Th1 Autoimmune Disease via Deviation to the Th2 Pathway
Article in Immunity
Volume 15, 15-22, July 2001
Immunomodulation of Experimental Autoimmune Encephalmyelitis with Ordered Peptides Based on MHC-TCR Binding Motifs
Article in The Journal of Immunology
2001, 167:2688-2693
Suppressive Immunization with DNA Encoding a Self-Peptide Prevents Autoimmune Disease: Modulation of T Cell Costimulation
Article in The Journal of Immunology
1999, 162:3336-3341
Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes Off
Article in Science
Volume 280. 10 April 1998
Suppressive Vaccination with DNA Encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity
Article in Nature Medicine
Volume 2, Number 8, August 1996
