Phase 2 Trial DNA Vaccine Encoding Myelin Basic Protein for Multiple Sclerosis
Article in Annals of Neurology, In Press




“Induction of Antigen-Specific Tolerance in Multiple Sclerosis After
Immunization With DNA Encoding Myelin Basic Protein in a Randomized,
Placebo-Controlled Phase 1/2 Trial”
Article in Archives of Neurology
VOL 64 (NO. 10), pp. 1407-1415, October 2007




“Phase I/II trial of a MBP encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin for treatment of MS”
Poster number PP14-22 presented at the 8th International Congress of Neuroimmunology, Nagoya, Japan, October 15-19, 2006




Antigen-specific immunomodulation in multiple sclerosis patients treated with MBP
encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin
Poster presented at 21st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Thessaloniki, Greece, September 28 – October 1, 2005.




Antigen-Specific Therapies in Multiple Sclerosis: Going Beyond Proteins and Peptides
International Reviews of Immunology, 24:415-446, 2005




An Immunomodulatory GpG Oligonucleotide for the Treatment of Autoimmunity via the Innate and Adaptive Immune Systems.
Article in The Journal of Immunology, 2003, 171: 4920-4926




Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
Article in Nature, Biotechnology
Volume 21, Issue 9, September 2003




Autoantigen microarrays for multiplex characterization of autoantibody responses
Article in Nature Medicine
Volume 8 Number 3 March 2002

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination
Article in Proceedings National Academy of Sciences
February 18, 2003, Vol. 100, No 4, 1867 - 1872

The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease
Article in Science
Vol. 294 23 November 2001

Immunization with DNA Encoding an Immunodominant Peptide of Insulin Prevents Diabetes in NOD Mice
Article in Clinical Immunology
Vol. 100, No.2, August, pp. 164-171, 2001




Combination of Gene Delivery and DNA Vaccination to Protect from and Reverse Th1 Autoimmune Disease via Deviation to the Th2 Pathway
Article in Immunity
Vol. 15, 15-22, July 2001




Immunomodulation of Experimental Autoimmune Encephalmyelitis with Ordered Peptides Based on MHC-TCR Binding Motifs
Article in The Journal of Immunology
2001, 167:2688-2693




Suppressive Immunization with DNA Encoding a Self-Peptide Prevents Autoimmune Disease: Modulation of T Cell Costimulation
Article in The Journal of Immunology
1999, 162:3336-3341




Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes Off
Article in Science
Vol. 280. 10 April 1998




Suppressive Vaccination with DNA Encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity
Article in Nature Medicine
Volume 2, Number 8, August 1996